Kidney Health & Complex Illness

Evidence-informed articles and clinical insights on chronic kidney disease, renal health, complex chronic illness, mould-related illness, nutrition and naturopathic medicine.

Adrian Harper Adrian Harper

Why SIBO Keeps Coming Back: Understanding Recurrence and the Underlying Causes

SIBO often returns because treatment reduces microbial overgrowth without correcting the factors that allowed it to develop. This article explores the role of impaired motility, constipation, methane, diet, medications, mould-related illness and chronic kidney disease, and explains how I approach recurrent SIBO from an evidence-informed naturopathic perspective.

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Adrian Harper Adrian Harper

Peptides and Chronic Kidney Disease: Can They Restore Kidney Function?

Peptides are increasingly promoted as regenerative therapies for chronic kidney disease, but the evidence is still emerging. While experimental research into compounds such as Klotho-derived peptides, apelin, elamipretide and BPC-157 is scientifically interesting, there is currently little evidence that commercially available peptides can restore kidney function in humans. This article looks at the research, the limitations, and the additional risks associated with unapproved peptide products sold online.

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Adrian Harper Adrian Harper

Supplements and Herbal Medicines in Kidney Disease: Are They Safe?

When living with kidney disease, asking if a supplement is universally "safe" rarely yields a simple yes or no answer. From altered nutrient clearance in chronic kidney disease to complex drug interactions after a transplant, supplement safety depends entirely on your specific stage, current blood work, and dosages. Rather than avoiding supplements altogether or taking unverified products, discover how to evaluate what is truly appropriate for your unique kidney health journey.

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Adrian Harper Adrian Harper

Microplastics and Kidney Disease: The Evidence So Far

Microplastics are now being detected within human kidney tissue, while emerging research suggests they may contribute to oxidative stress, inflammation and fibrosis. This article examines what the evidence currently shows about microplastics, chronic kidney disease and dialysis — and where important uncertainties remain.

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Adrian Harper Adrian Harper

Assessing Your Home for Mould

Concerned that hidden mould or water damage in your home may be contributing to ongoing symptoms? This article explains what to look for, how ERMI and environmental testing can help, what a building assessment involves, and how findings can guide remediation..

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Adrian Harper Adrian Harper

Constipation and Kidney Disease: Why Bowel Motility Matters

Constipation is common in chronic kidney disease and becomes increasingly prevalent as kidney function declines. Research suggests the relationship may work both ways, with slower bowel transit potentially influencing gut-derived uraemic toxins, while CKD, dialysis, diet and medications can all affect bowel motility. This article explores why bowel regularity matters across CKD, dialysis and kidney transplantation.

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Adrian Harper Adrian Harper

Phosphorus and Kidney Disease: Do You Really Need a Low-Phosphorus Diet?

Phosphorus management in chronic kidney disease is more complex than simply avoiding high-phosphorus foods. This article explores phosphate additives, phosphorus bioavailability, plant and animal sources, and when dietary restriction is actually needed across CKD, dialysis and transplantation.

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Adrian Harper Adrian Harper

Is Mould Exposure Making You Sick? Understanding the Spectrum of Mould-Related Illness

Mould-related illness is not a single condition. Exposure to damp or water-damaged buildings may contribute to allergic and respiratory symptoms, mast-cell activation or the broader multisystem illness associated with CIRS. Understanding the pattern of symptoms, when they began and their relationship to a particular environment can help determine whether mould exposure warrants further investigation.

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Adrian Harper Adrian Harper

Understanding eGFR and Creatinine: What Do Your Kidney Results Actually Mean?

eGFR and creatinine are central markers of kidney function, but individual results can fluctuate for reasons that do not necessarily reflect true progression or recovery. This article explains what these tests actually measure, why hydration, exercise, muscle mass and creatine can affect results, and how to interpret kidney function more accurately over time.

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Adrian Harper Adrian Harper

The Impact of Microplastics on Gut Health: An Emerging Concern

In recent years, the intersection between environmental pollution and human health has become a focal point of scientific research. A recent article published in the World Journal of Gastroenterology, entitled “Impact of Microplastics and Nanoplastics on Liver Health: Current Understanding and Future Research Directions,” delves into a crucial aspect of this intersection – the interaction between microplastics (MPs) and gut microbiota.

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