Mould Biotoxin Illness (CIRS)

Mould Biotoxin Illness is a multi-symptoms, multi-system, inflammatory syndrome due most commonly to exposure to mould biotoxins from water-damaged buildings. Other sources of environmental biotoxins include blue-green algae, dinoflagellate, and some tick-borne infections. Chronic Inflammatory Response Syndrome (CIRS) was first described by Dr. Ritchie Shoemaker, a U.S. physician who developed the Shoemaker Protocol for the treatment of CIRS. Approximately 95% of people who develop CIRS have a genetic susceptibility that results in an inability to clear biotoxins from the body post-exposure. The biotoxins persist in the system, triggering a chronic pattern of immune dysregulation.

It’s common to experience a range of symptoms with CIRS. If you are experiencing symptoms from 6 or more of the below symptom clusters, CIRS investigations are warranted.

  • Fatigue
  • Weakness, Decreased Assimilation of New Knowledge, Aches, Headaches, Light Sensitivity
  • Memory Impairment, Decreased Word-finding
  • Difficulty Concentrating
  • Joint Pain, Morning Stiffness, Cramps
  • Tingling, Tremors, Unusual Pain, Unusual Skin Sensitivity
  • Shortness of Breath, Sinus Congestion
  • Cough, Excessive Thirst, Cofusion
  • Appetite Swings, Difficulty Regulating Temperature, Urinary Frequency
  • Red Eyes, Blurred Vision, Sweats, Mood Swings, Ice-pick Pains
  • Abdominal Pain, Diarrhoea, Numbness
  • Tearing of Eyes, Disorientation, Metallic Taste
  • Static Shocks, Vertigo

Adrian provides assessment for CIRS based on both the Shoemaker Protocol and appropriate functional pathology. These may include:

  • Biotoxin Questionnaire
  • Visual Contrast Screening
  • HLA DQ-DR Genotype for Genetic Susceptibility
  • MARCoNS (Multi-Antibiotic Resistant Coagulase Negative Staphylocci Infection)
  • Biotoxin Panel: C3a, C4a, MMP-9, MSH, PAI-1, TGF beta-1, VEG-F, VIP, Leptin, ADH, Osmolality
  • Androgen Studies
  • GPL-MycoTox Screen
  • SIBO and Microbiome Testing

Adrian will advise on the most appropriate CIRS testing based on your presenting symptoms and health history. A treatment plan will then be developed to remove the exposure, clear biotoxins from the system and restore general health. Adrian will collaborate as needed with other health practitioners, including integrative GPs.